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A study involving 441 participants found that the fecal microbiota diversity of young CRC patients was significantly lower than that of healthy controls ( p = 0.0074), and the abundance of butyrate-producing bacteria (such as Faecalibacterium prausnitzii and Eubacterium rectale ) was significantly reduced (Kong et al., 2023)

Oct 16 2009;16:94

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Given the ability of ALCAR to hinder CCL2 production in PCa and BPH cell lines, we also investigated effects of PCa conditioned media with or without ALCAR on CCR2 expression by endothelial cells, to assess paracrine mechanisms