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ERS activates a series of cascading reaction pathways, regulating the formation of intracellular iron ions and ROS through iron metabolism, Xc-/GPX4 system (Zhao et al., 2021), lipid metabolism (Tak et al., 2022), and other ferroptosis pathways such as p62-Keap1-NRF2, p53-SAT1-ALOX15, ATG5-ATG7-NCOA4, and glutaminolysis (Lane et al., 2018), playing a dual role in ferroptosis
690 The effects were confirmed by in vivo treatment of obese KK-Ay mice fed with a high-fat diet, resulting in decreased levels of triglycerides in both plasma and liver
Acidity-triggered charge-convertible nanoparticles that can cause bacterium-specific aggregation in situ to enhance photothermal ablation of focal infection
