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The typical symptoms include executive dysfunction, mental slowness, memory deficit, behavioral disturbances, and depression, although they depend on the type, severity, extent, and location of the underlying cerebrovascular pathology [77,78]

The STOP-Bang questionnaire, with eight items, screens for obstructive sleep apnea (OSA), with scores of 3 or above indicating moderate to severe OSA

Hyperglycemia-treated Schwann cells release pathologic EVs that suppress axonal growth in vitro and accelerate DPN development in vivo in db/db T2D mice