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Although the mechanism by which cuprizone exerts its effects remains controversial 72,73 , it has been recently shown that cuprizone decreases copper in affected CNS areas and is recovered with improved copper bioavailability 74

Antioxidant activity The main function of -tocopherol in humans is that of a fat-soluble antioxidant that stops lipid peroxidation

10.3390/antiox11030503 17 BorgesS.OdilaJ.VossG.MartinsR.RosaA.CoutoJ

In this Review, we highlight such non-canonical targets in preclinical MS research with a focus on five highly promising areas: oligodendrocytes
