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Meet Our Experts Simran Malhotra, MD Medical Reviewer Member of American College of Lifestyle Medicine Simran Malhotra, MD, DipABLM, CHWC, is a triple board-certified physician in internal medicine, hospice and palliative care, and lifestyle medicine, as well as a certified health a

Though the exact mechanism is not well understood, it is thought that estrogen deficiency leads to down regulation of the expression of transcellular calcium transport proteins plasma membrane calcium pump 1b (PMCA1b), transient receptor potential cation channel subfamily V member 5 (TRPV5) and calbindin-D 28K (CaBP28k) [95]

Graphical depictions of self-report temperature data Figure 1 illustrates the differences in average self-reported body temperature across participants with average PROMIS depression symptom T-scores WNL, and in the mild, moderate, and severe ranges