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AOs also impair glucose uptake in cortical and hippocampal neurons via 4-hydroxynonenal, reducing ATP levels and leading to glucose transporter 3 (GLUT3) binding and lipid peroxidation (Mark et al., 1997)
Asia Pacific Decentralized Clinical Trials Market Trends Asia Pacific accounts for 25.4% of the 2025 global DCT market and leads all regions in CAGR at 14%, driven by rapidly expanding clinical trial infrastructure in China and India alongside progressive regulatory evolution across Japan, Australia, and South Korea
human evidence for this combination is limited and results vary
