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The energy necessary for the transport of these neurotransmitters into the secretory vesicles is provided by the proton gradient generated by the vacuolar H + -ATPase (V-ATPase)
Mitochondrial respiration reduces exposure of the nucleus to oxygen
Other subcellular sources of ROS are also possible as plasma metabolomic profiling has suggested peroxisomal dysfunction in ME/CFS patients (18)
Ghanem E
