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When using clarified cell lysates, each lysate was added to 5% of the reaction volume

Bibcode:1995JBiCh.270.7176K

Specifically, analysis of Gdf11 -null mice revealed that the majority of these mice experience complete renal agenesis and failure of ureteric bud outgrowth from the Wolffian duct 53

It's crucial for the skin cells to grow and divide properly so that new cells could form and preserve skin elasticity
