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A distinguishing feature is that the affected area is typically tender to touch, which differentiates it from many cardiac conditions

Traditionally used to improve facial appearance through the elimination of fine lines and wrinkles, BOTOX treatment is also FDA-approved to treat other conditions such as facial tics and spasms, dystonia and bladder dysfunction in addition to migraines

[DOI] [PMC free article] [PubMed] [Google Scholar] 69.Kolenda J., Jensen S.S., Aaberg-Jessen C., Christensen K., Andersen C., Brnner N., Kristensen B.W

Divalent metal cations are found to facilitate ligand orientation and ion coordination
