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This can induce chronic inflammation and genomic instability, thus forming a pro-tumor microenvironment (62, 63)

These patients should be treated prophylactically with a nucleoside analogue, which should be continued for 6 months after immunosuppressive therapy is completed

in RHM, the NADH consumption reaction has lower activity and therefore has higher control, meanwhile, in RLM, the NADH production reactions are the ones with lower activity and therefore the ones with higher control

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