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Neuroinvasion could cause demyelination and axonal damage, leading to GBS manifestations

J Nippon Med Sch

In obesity, the malfunction of adipose tissue with exceeded energy intake over the energy expenditure triggers metabolic stress, which leads to increased inflammatory responses, which then results in the interrelated complications including glucose intolerance, hypertension, insulin resistance, dyslipidemia, liver diseases, stroke and cancer

In addition, exosomal KG attenuated signal transducers and transduction-3 (STAT3)/NF-B activators through its receptor 1 oxoglutarate (OXGR1) in adipocytes
