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Thus, in the absence of a healthy glycocalyx, excess sodium ions enter endothelial cells and activate cell signaling pathways that positively regulate production of F-actin cytoskeletal fibers (85)
10.1093/ajcn/nqab262 Am J Clin Nutr
As more insights on aging mechanisms have been uncovered, these hallmarks have been expanded upon to include disabled macroautophagy/compromised autophagy, chronic inflammation, and dysbiosis (Guo et al., 2022
