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Differential gene expression analysis revealed a continuous trajectory of transcriptional changes with stage of disease progression from MASLD to advanced MASH (Supplemental Figure 7, A and B), indicating substantial transcriptional remodeling during MASLD/MASH progression

73 In another case report, a 64-year-old man presented with acute respiratory distress syndrome due to COVID-19 severe pneumonia and secondary bacterial lung infection was admitted to Taihe Hospital in Shiyan, China and was given repeated bedside bronchoscopy at intervals of 1 day or 2 days with a large dose of 10,00015,000 mg/time of N-acetylcysteine nebulized inhalation solution lavage combined with routine nebulization and sputum suction airway management

This supports the hypothesis that meningococcal translocation across brain barriers occurs primarily through the endothelium, without the active participation of immune cells