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In another study of patients with left ventricular dysfunction, supplementation with 150 mg/day of coenzyme Q 10 for four weeks before cardiac surgery increased coenzyme Q 10 concentrations in the heart but not in skeletal muscle (107)

However, blocking both processes nearly abolished MOR desensitization
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Moreover, 3 trials had a high risk of bias regarding blinding of participants, personnel [9,24,31], and 3 trials had low-risk outcome assessors [22,29,34]
