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Interestingly, therapeutic targeting not only includes GI disorders and enteric infections but certain systemic diseases as well, including mineral metabolic disorders (hyperphosphatemia, hyperkalemia, or sodium overload) and diabetes

In experimental systems, DSIP has been shown to influence second messenger activity and hormonal signaling cascades linked to the hypothalamicpituitaryadrenal axis, including regulation of adrenocorticotropic hormone and related endocrine mediators [4]

(Lee told Undark that more research is underway, including one larger study and another with a comparison group.) If we do some certain studies, he said, the FDA may say, youve shown safety and efficacy. The agency, he added, might then allow the peptides to be compounded: Thats all were asking, he said

Research on Pseudomonas aeruginosa , a major biofilm-forming pathogen in cystic fibrosis, has shown that LL-37 at physiological concentrations can significantly reduce biofilm thickness and bacterial survival within