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A study of the subcellular localization of GPx1 variants to appreciate the molecular consequences associated with diseases demonstrated that the primary sequence of GPx1 affects subcellular localization and that the sequence and cell location can be important to understand the impact of GPx1 on human diseases, including cancer [24]
Br J Clin Pharmacol 2000

10.3164/jcbn.17-139 73 ZhangY.JiaJ.DingY.MaY.ShangP.LiuT.et al (2016)
In my own clinical practice, I already recommend a full blood count as part of annual review, to ensure that the person is not anaemic and, thus, that the HbA 1c is reliable, but this also proves useful to assess MCV in this context
