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Moreover, the damage to DNA caused by excessive ROS activates apoptotic pathways to accelerate neuronal cell death (Wang et al., 2021a

Potential future therapeutic options of autoimmune myositis The group of idiopathic inflammatory myopathies consists of heterogeneous disorders, such as polymyositis, dermatomyositis, antisynthetase syndrome, immune-mediated necrotizing myopathy, inclusion body myositis, and overlap myositis syndromes (143)

However, it is now being firmly established that deletions in the chromosome 21 are commonly discovered in some patients with intellectual disability including ASD (Hogart et al., 2010)