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However, we are also aware of the potential medication interactions that can occur with this treatment

In white adipose tissue, blocking NNMT elevated resting calorie burn, decreased adiposity, and improved insulin sensitivity in rodent models, independent of diet or activity changes (Kraus et al., Nature Medicine )

Published research has demonstrated that NNMT expression is significantly elevated in white adipose tissue of obese individuals compared to lean controls

Among the most important ones are traumatic brain injury and diabetes mellitus
