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Description
Compounded medications are essential in modern healthcare, filling gaps when FDA-approved drugs are unavailable, in shortage, or require customization
( GAP1 expression from its native promoter would not serve as a good control here because pGAP1 is repressed by the ammonium sulphate N-source and so D-HIS would not be taken up by the cells)
Normal or high levels do not always rule out methylation impairment, but help determine whether symptoms are due to deficiency versus impaired utilization or clearance
