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Additional information Publisher's note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations

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[4] Pharmacokinetics and Distribution Pharmacokinetic work in mice reported systemic exposure and distribution of 5-Amino-1MQ to metabolically active tissues, including adipose, muscle, and liver, after subcutaneous compound application

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NNMT, nicotinamide N-methyltransferase, is found throughout the body but is particularly active in fat tissue

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Collectively, these results provide a novel foundation for future investigations

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