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The efficacy of evexomostat in inhibiting the angiogenic proteins FGF (Fibroblast growth factors) and VEGF (Vascular endothelial growth factor) was validated in a phase I clinical trial in advanced solid tumors (NCT02743637)

NicholsonJKHolmesEKinrossJBurcelinRGibsonGJiaWet al

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Thus, a study on propolis, a possible kidney-sparing drug, reported that it protects the kidney from free radicals and some adverse effects, through repairing the SOD activity, GSH, and MDA levels [23]