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Description
ACSL4, an enzyme that converts fatty acid to fatty acyl-CoA esters, is known to dictate ferroptosis sensitivity by shaping cellular lipid composition (27) and contributes to intestinal tissue injury (68)

However, NO and ROS can independently release cytochrome c from mitochondria, affecting the caspase-like signalling pathway that leads to HR (Mur et al., 2006)

Furthermore, PSAT1 regulates changes in the level of glutamine-derived -KG, which controls mESC pluripotency and differentiation 106

Mol Psychiatry 27 , 13501361 (2022)
