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Description
In the absence of myelin, redistribution of Na + occurs to maintain the transmission of nerve impulses that increases energy demand, and this produces a situation of virtual hypoxia. At the end, the demand exceeds the capacity of axonal mitochondria to produce enough ATP, which causes an increase in the concentration of Ca 2+ in the axon
Any percentage higher than 2% might become goopy and tacky
doi:10.1038/s41467-019-09192-z
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