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Accessed May 30, 2026

106 Melatonin not only regulates circadian rhythms like the sleep and wake cycle, it also reduces skin oxidative stress and inflammation, protects skin against solar radiation damage, and appears to promote wound healing and skin barrier health

Histopathological studies reveal that CQ group and CQ combined with L-ARG group showed vigorous morphological changes i.e., deformed epidermis and cells, increased epidermal thickness, vacuolization and loss of membrane integrity

[DOI] [PubMed] [Google Scholar] 316.Luo Y, Chen G-L, Hannemann N, Ipseiz N, Krnke G, Buerle T, Munos L, Wirtz S, Schett G, Bozec A
