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Active smoking is associated with the development of adverse events of biological therapy in patients with inflammatory bowel disease

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Most likely, considering the described effects of BPC 157, and its specific effect on NO/prostaglandins that occurred rapidly, it might be distinctive from the relations of the phosphatase and tensin homologue (PTEN) inhibitor, the bisperoxovanadium activation of PI3K/AKT-mTOR signaling [97], or the methylprednisolone inhibition of TNF-alpha expression and NF-kB activation [94]