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The exceptions are kisspeptin (dosed per kg in research settings) and some practitioners who adjust TB-500 loading doses for users over 250 lbs (increasing from 5 mg to 7.5 mg twice weekly)

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Berberine also has anti-inflammatory immunomodulatory effects: studies have shown that berberine antagonizes pro-inflammatory signaling pathways and inhibits immune cells from overproducing cytokines such as TNF-, IL-6, and IL-1 (94)