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Some researchers found that those with high B12 levels have shorter lifespans

doi: 10.1016/j.xphs.2019.10.046 20 LuxAYuXScanlanCNNimmerjahnF

Injury to the peripheral nervous system causes hyperactivity of ACC neurons and upregulation of Piezo1 expression, thus supporting the involvement of Piezo1 channels in pain information transmission

However, scientists dont fully understand the underlying mechanisms that drive these effects
