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In 1901, the French Neurologist Pierre Marie (18531940) established the concept of lacunar infarct, that he clearly distinguished from the tat cribl previously reported by Durand-Fardell

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Artificial food colorings (such as tartrazine/Yellow 5, Red 40) and synthetic chemical preservatives may also irritate the gut lining in sensitive individuals, contributing to the kind of gut dysbiosis directly linked to worsened vitiligo in 2025 research