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Regeneration of the lung alveolus by an evolutionarily conserved epithelial progenitor
NAD + can be generated de novo in the kynurenine pathway, where Trp is oxygenated to N-formylkynurenine by tryptophan 2,3-dioxygenase (TDO) or indoleamine 2,3-dioxygenase (IDO) 31
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