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10.1172/JCI34613 [DOI] [PMC free article] [PubMed] [Google Scholar] 125.Wiley NJ, Madhankumar A, Mitchell RM, Neely EB, Rizk E, Douds GL, et al

The peptides effects on multiple neurotransmitter systems create potential for interactions

High glycolytic activities in PC are inversely correlated with the effectiveness of radiation, and elevated DNA damage responses in cancer cells are involved in changes in the process (259262)

Tumor heterogeneity presents a significant challenge, as numerous cancers are deficient or have mutated for essential necroptosis regulators such as RIPK3 or MLKL, which restricts the effectiveness of necroptosis inducers
