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Accordingly, glutamine deprivation selectively induces apoptosis in MYC-amplified cancer cells (Qing et al., 2012)
Recognition of RNA N 6 -methyladenosine by IGF2BP proteins enhances mRNA stability and translation
This analogy enables us to metaphorically describe downregulation and desensitization as phenomena that make the systems more resilient in responding to ligand perturbations thereby improving the stability of the system resting state
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