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Lang CA, et al
Cysteine is frequently identified as rate-limiting, which provides the rationale of why N-acetylcysteine (NAC) is frequently studied and suggested as a supplement for glutathione support [50], yet a review of the data indicates its use may be inconclusive or equivocal
doi: 10.1021/cr400546e
In fact, PFKFB3 is essential for the necessary lamellipodia formation in endothelial cells 75
