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As a critical pro-inflammatory factor, NF-B, plays an important role between the inflammatory response to skeletal muscle atrophy after SCI and the balance of apoptotic and anti-apoptotic signaling, on the one hand, and determines whether cells will undergo apoptosis in response to other apoptosis-inducing-related factors such as TNF- and TWEAK, affecting the proliferation and survival of skeletal muscle cells (83)

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