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Ibrexafungerp (SCY-078, MK-3118, ClinicalTrials.gov Identifier: NCT03059992) is a triterpenoid antifungal also inhibiting the biosynthesis of -(1,3)-D-glucan (227)

NF1 is a multisystemic disease that requires multidisciplinary follow-up with dermatologists playing an important role

Therefore, the authors suggest that this association could act by a synergic effect increasing the neuroprotective action of MEM and, overall, providing a more complete protection in patients exposed to glutamatergic excitotoxicity

In order to improve the effect of gene therapy in regulating ferroptosis in OA, many studies in recent years have been devoted to optimizing the delivery system to overcome the complexity and barriers of the intra-articular environment (180)