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Description
One such agent is Olorofim, a dihydroorotate dehydrogenase inhibitor currently in advanced clinical development, which impairs mitochondrial pyrimidine biosynthesis, leading to defective DNA synthesis and subsequent fungal cell death (Oliver et al., 2016)

Gene-for-gene defense of wheat against the Hessian fly lacks a classical oxidative burst

Flavonoids like quercetin and naringenin have also improved motor functions in toxinbased models, attributed to their antioxidative and antiapoptotic effects

doi: 10.1515/CCLM.2002.232
