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In their study, high-dose anti-VEGFR2 treatment aggravated intratumoral hypoxia and restrained the infiltration of CD8 + T cells into the TME, thereby suppressing anti-cancer immunity
An ideal antioxidant should be readily absorbed, remove RONs and, eventually, chelate metals at physiologically suitable concentrations [7,8]
Mutations in persulfite dioxygenase, oxidizing GSSH to sulfite and GSH, are bases for autosomal-recessive inherited ethylmalonic encephalopathy [112]
Therefore, it obtains purine nucleosides only via the purine salvage route (Liechti and Goldberg 2012
