glutathione synthetase deficiency omim Multiple congenital anomalies in two fetuses with glutathione‐synthetase deficit (GSS) - Jury - 2024 - Clinical Genetics Impaired Glutathione Synthesis in Neurodegeneration
Description
212 FBXO31 enhances cisplatin-induced ferroptosis in cholangiocarcinoma cells and stem cell-like cells, and the mechanism may be related to increased GPX4 ubiquitination and proteasome degradation, which could be reversed by GPX4 overexpression

Currently, hormetic nutrients and agents modulating vitagenes are also drawing increasing attention of inhibiting ferroptosis due to their protection against oxidative stress and neuroinflammation in CNS diseases

Oral supplementation of glutamine attenuates the progression of nonalcoholic steatohepatitis in C57BL/6J mice

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