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Although the precise mechanisms remain to be fully elucidated, recent studies have suggested that DSF exerts its anti-cancer function by inducing reactive oxygen species (ROS)-dependent oxidative stress and apoptosis [21], inhibiting proteasome activity [22], and modulating tumor immune microenvironment [23]

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2011;2 doi: 10.3389/fphys.2011.00104

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Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer

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