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Vitamin B12 therapy may also be considered in individuals with conditions such as Lyme disease, osteoporosis, tendonitis, liver or kidney disorders, asthma, and certain neurological or psychiatric conditions

Patients often report a gradual but positive change over weeks of therapy

If low levels of B 12 remain for a long time, the condition also can lead to irreversible damage to nerve cells, which can cause the following symptoms: numbness and tingling in the hands and feet difficulty walking muscle weakness irritability memory loss dementia depression psychosis

There is a mean decrease in intragastric acidity after 24 hours after intravenous administration