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Description
The incidence of renal failure in clinical studies in which patients received ALIMTA as a single agent ranged from 0.4% to 0.6% (Studies JMEN, PARAMOUNT, and JMEI [see Adverse Reactions (6.1)]

Vomiting occurs less frequently than nausea but can be problematic when it does occur, particularly if it leads to dehydration or interferes with nutrition and medication absorption

This targeted uptake in diseased tissue is a genuinely unusual pharmacological property that makes KPV particularly well-suited to inflammation-driven gut conditions like ulcerative colitis and IBD

Dor, J.L
