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Description
MAFLD is now the most prevalent chronic liver disease globally, affecting nearly one-quarter of the global population [1,2]
Additionally, fasting triglyceride levels were lower
Although one of these sites is located in the 5 promoter region and the other site in the 3 flanking region, both sites are functional, as they have both been shown to bind the PU.1 nuclear factor in gel mobility shift assays, and both mediate transcription, as assessed by reporter gene assays
doi: 10.1371/journal.pone.0178614
