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Description
This fact is relevant as transgenic mice overexpressing IGFBP-2 were resistant to developing obesity when fed with high fat diet [174], suggesting that this molecule could have a direct effect on preadipocyte differentiation

No genetic test predicts exact response to any single intervention

Treatment modalities are reviewed, including hormonal therapies, insulin sensitizers, anti-androgens, lifestyle changes, as well as emerging therapies like agents that target the neuroimmune system and metabolic pathways

Ann Neurol 15(Suppl):S119S125 Berent S, Giordani B, Lehtinen S, Markel D, Penney JB, Buchtel HA et al (1988) Positron emission tomographic scan investigations of huntingtons disease: cerebral metabolic correlates of cognitive function
