glutathione for catalyzing disulfide formation Deciphering the mechanism of glutaredoxin-catalyzed roGFP2 redox sensing reveals a ternary complex with protein reduction Formation and transfer of disulphide
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The development of such agents will be necessary to further investigate the potential for targeting GPX4 in cancer in vivo

Zhang L, Zheng Y, Cheng X, Meng M, Luo Y, Li B

These results illustrated that macrophage-derived EVs possess the ability to sequester and remove iron from biological samples, making them a promising candidate for iron chelation therapy

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