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11 , 12 , 13 , 14 Isatuximab is approved for the treatment of adult patients with RRMM in combination with pomalidomide and dexamethasone (Pd), and in combination with carfilzomib and dexamethasone (Kd), in patients who have received at least two prior therapies, including lenalidomide and a PI, or who have received onethree prior lines of therapy, respectively

Chao X, Wang S, Ding W-X

J Neurochem 18:513519 Calabrese V, Scapagnini G, Ravagna A, Fariello RG, Giuffrida Stella AM, Abraham NG (2002) Regional distribution of heme oxygenase, HSP70, and glutathione in brain: relevance for endogenous oxidant/antioxidant balance and stress tolerance

However, its potency can also lead to potential side effects if not used correctly