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Description
Its research relevance comes from interest in how senescent cells maintain survival signaling under stress conditions
Complexity: Its association with enzyme-related pathways makes it appealing to individuals who prefer structurally advanced molecules

We demonstrate in a humanised FcRn/albumin double transgenic mouse model (AlbuMus) the ability to tune half-life based on the albumin sequence fused with a BiTE-like bispecific (anti-EGFR nanobody x anti-CD3 scFv) light T-cell engager (LiTE) construct [(t 0.6 h (Fc-less LiTE), t 19 hours (Albu-LiTE-NB), t 26 hours (Albu-LiTE-WT), t 37 hours (Albu-LiTE-HB)]

Particularly for those on topical steroids, abrupt cessation can trigger severe rebound flares that make peptide assessment impossible
