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Several dug therapies have been trialed for treatment of JHR in spirochetal infections but their benefit is limited
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Bach1 induces the accumulation of lactate-mediated H4K12 lactylation at the promoter region of LRRC15, targeting CD248/GP130/JAK-STAT3 axis to influence the development of astrocytes [181]
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The amylin pathway represents a fundamentally different approach than GLP-1 agonists, making it complementary rather than redundant
