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Citrulline and arginosuccinic acid are increased on plasma amino acid chromatography.20 This is the only UCD where there is a high rate of neurologic complications even without hyperammonemia and a progressive chronic liver disease and hepatic fibrosis21

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In experimental models, diabetes reduces NGF expression in target tissues including skin and muscle, impairing retrograde transport to neuronal cell bodies and decreasing neuropeptides such as substance P and calcitonin gene-related peptide [146]

En plus de soutenir la forme physique, lActyl L-Carnitine peut galement tre utile pour amliorer la fonction mentale et soutenir la mmoire et la concentration : cette molcule est en effet prsente aussi au niveau crbral, o elle joue un rle important dans la production dnergie et la protection des cellules nerveuses contre le stress oxydatif