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10.1111/ddg.14177 J Deutschen Dermatol Gesellschaft
Results from phase I/II study of the combination of oral rigosertib and azacitidine in patients with myelodysplastic syndromes
Two very recent studies show that high-dose VitC synergizes with immune checkpoint inhibitors (ICI) anti-PD-1 and anti-CTL-4 in mouse models, as well as increases the immunogenicity of effector T cells [90, 91]
Therefore, these cataracts are not caused by loss of the normal function of the mutant proteins, but by the acquisition of an abnormal function
