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Description
This deterioration of brain function is due to the livers incapacity to remove blood toxins, such as ammonia and lipopolysaccharides, which causes systemic inflammation and activation of the circulatory neutrophils [146]
Nature 1972
With no cutting or invasive techniques involved, the chance of complications is very low

Piezo1 expression increases in astrocytes in response to increased nerve inflammation (Velasco-Estevez et al., 2020)