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McCann MR, Tamplin OJ, Rossant J, Sguin CA

Elife 4 , e07938 (2015)

VEGF, in addition to acting as a mitogenic signal for vascular endothelial cells, protects tumor vasculature from apoptosis by inducing anti-apoptotic factors, mediates the activation of extracellular matrix degrading enzymes, and promotes tumor-immune evasion by recruiting immunosuppressive cells such as Tregs, TAMs, and MDSCs

[DOI] [PMC free article] [PubMed] [Google Scholar] 7.Sikiric P., Hahm K.B., Blagaic A.B., Tvrdeic A., Pavlov K.H., Petrovic A., Kokot A., Gojkovic S., Krezic I., Drmic D., et al